Y68S (p.Tyr68Ser) variant of KRT16 (Keratin, type I cytoskeletal 16)
Y68S (p.Tyr68Ser) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
Y68S (p.Tyr68Ser) variant details
- p.Tyr68Ser
- ExAC rs749376152
- TOPMed rs749376152
- gnomAD rs749376152
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.16
- CADD 16.00
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available