R41P (p.Arg41Pro) variant of KRT16 (Keratin, type I cytoskeletal 16)
R41P (p.Arg41Pro) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R41P (p.Arg41Pro) variant details
- p.Arg41Pro
- ExAC rs1133106
- TOPMed rs1133106
- gnomAD rs1133106
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.56
- CADD 22.80
- PolyPhen-2 0.65
- SIFT 0.01
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available