L98F (p.Leu98Phe) variant of KRT16 (Keratin, type I cytoskeletal 16)
L98F (p.Leu98Phe) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
L98F (p.Leu98Phe) variant details
- p.Leu98Phe
- ExAC rs780644845
- gnomAD rs780644845
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.20
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 0.71
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available