K15E (p.Lys15Glu) variant of KRT16 (Keratin, type I cytoskeletal 16)
K15E (p.Lys15Glu) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
K15E (p.Lys15Glu) variant details
- p.Lys15Glu
- gnomAD rs267607409
- Missense
- Variant Prioritization Score for Impact Estimate 0.39
- REVEL 0.30
- CADD 24.20
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available