G99D (p.Gly99Asp) variant of KRT16 (Keratin, type I cytoskeletal 16)
G99D (p.Gly99Asp) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
G99D (p.Gly99Asp) variant details
- p.Gly99Asp
- Ensembl rs1908235657
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.41
- CADD 16.80
- PolyPhen-2 0.31
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available