G97V (p.Gly97Val) variant of KRT16 (Keratin, type I cytoskeletal 16)
G97V (p.Gly97Val) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G97V (p.Gly97Val) variant details
- p.Gly97Val
- TOPMed rs1338121048
- gnomAD rs1338121048
- Missense
- Variant Prioritization Score for Impact Estimate 0.465
- REVEL 0.56
- CADD 20.50
- PolyPhen-2 0.61
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 0.00012)
- Structural context available