G87C (p.Gly87Cys) variant of KRT16 (Keratin, type I cytoskeletal 16)
G87C (p.Gly87Cys) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
G87C (p.Gly87Cys) variant details
- p.Gly87Cys
- gnomAD rs1490942621
- Missense
- Variant Prioritization Score for Impact Estimate 0.361
- REVEL 0.34
- CADD 22.70
- PolyPhen-2 0.82
- SIFT 0.02
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available