G84E (p.Gly84Glu) variant of KRT16 (Keratin, type I cytoskeletal 16)
G84E (p.Gly84Glu) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G84E (p.Gly84Glu) variant details
- p.Gly84Glu
- TOPMed rs267604878
- gnomAD rs267604878
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.29
- CADD 15.80
- PolyPhen-2 0.07
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available