G83R (p.Gly83Arg) variant of KRT16 (Keratin, type I cytoskeletal 16)
G83R (p.Gly83Arg) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
G83R (p.Gly83Arg) variant details
- p.Gly83Arg
- ExAC rs765123824
- TOPMed rs765123824
- gnomAD rs765123824
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.43
- CADD 21.10
- PolyPhen-2 0.89
- SIFT 0.11
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available