G66C (p.Gly66Cys) variant of KRT16 (Keratin, type I cytoskeletal 16)
G66C (p.Gly66Cys) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
G66C (p.Gly66Cys) variant details
- p.Gly66Cys
- Ensembl rs1567745678
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.48
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.04
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available