G63W (p.Gly63Trp) variant of KRT16 (Keratin, type I cytoskeletal 16)
G63W (p.Gly63Trp) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G63W (p.Gly63Trp) variant details
- p.Gly63Trp
- ExAC rs773632453
- TOPMed rs773632453
- gnomAD rs773632453
- Missense
- Variant Prioritization Score for Impact Estimate 0.478
- REVEL 0.52
- CADD 22.60
- PolyPhen-2 0.99
- SIFT 0.09
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available