G63R (p.Gly63Arg) variant of KRT16 (Keratin, type I cytoskeletal 16)
G63R (p.Gly63Arg) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
G63R (p.Gly63Arg) variant details
- p.Gly63Arg
- ExAC rs773632453
- TOPMed rs773632453
- gnomAD rs773632453
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- REVEL 0.52
- CADD 21.80
- PolyPhen-2 0.83
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available