G25R (p.Gly25Arg) variant of KRT16 (Keratin, type I cytoskeletal 16)
G25R (p.Gly25Arg) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- ExAC rs780828113
- TOPMed rs780828113
- gnomAD rs780828113
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.15
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available