G21* (p.Gly21Ter) variant of KRT16 (Keratin, type I cytoskeletal 16)
G21* (p.Gly21Ter) in KRT16 (Keratin, type I cytoskeletal 16) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
G21* (p.Gly21Ter) variant details
- p.Gly21Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.429
- CADD 33.00
- UniProt: Variant assessed as somatic; high impact.
- Population evidence available
- Structural context available