F106S (p.Phe106Ser) variant of KRT16 (Keratin, type I cytoskeletal 16)
F106S (p.Phe106Ser) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
F106S (p.Phe106Ser) variant details
- p.Phe106Ser
- ExAC rs757466593
- TOPMed rs757466593
- gnomAD rs757466593
- Missense
- Variant Prioritization Score for Impact Estimate 0.257
- REVEL 0.19
- CADD 12.50
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available