A61T (p.Ala61Thr) variant of KRT16 (Keratin, type I cytoskeletal 16)
A61T (p.Ala61Thr) in KRT16 (Keratin, type I cytoskeletal 16) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
A61T (p.Ala61Thr) variant details
- p.Ala61Thr
- ExAC rs758996794
- gnomAD rs758996794
- Missense
- Variant Prioritization Score for Impact Estimate 0.22
- REVEL 0.06
- CADD 17.30
- PolyPhen-2 0.00
- SIFT 0.25
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available