V45V (p.Val45Val) variant of KRAS (GTPase KRas)
V45V (p.Val45Val) in KRAS (GTPase KRas) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V45V (p.Val45Val) variant details
- p.Val45Val
- rs1951407606
- gnomAD 12-25227389-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.294
- CADD 11.30
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.268
- Literature evidence available