V44V (p.Val44Val) variant of KRAS (GTPase KRas)
V44V (p.Val44Val) in KRAS (GTPase KRas) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
V44V (p.Val44Val) variant details
- p.Val44Val
- rs2141510481
- gnomAD 12-25227392-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.36
- CADD 12.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.398
- Literature evidence available