S39S (p.Ser39Ser) variant of KRAS (GTPase KRas)
S39S (p.Ser39Ser) in KRAS (GTPase KRas) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S39S (p.Ser39Ser) variant details
- p.Ser39Ser
- rs2141510554
- gnomAD 12-25227407-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.486
- CADD 11.20
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.599
- Literature evidence available