S39A (p.Ser39Ala) variant of KRAS (GTPase KRas)
S39A (p.Ser39Ala) in KRAS (GTPase KRas) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
S39A (p.Ser39Ala) variant details
- p.Ser39Ala
- gnomAD 12-25235216-CT-C
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.147
- CADD 4.63
- Population evidence available
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.599
- Literature evidence available