S17T (p.Ser17Thr) variant of KRAS (GTPase KRas)
S17T (p.Ser17Thr) in KRAS (GTPase KRas) is a missense change. Clinical records from ClinVar and UniProt describe it as uncertain significance in the context of Vascular malformation. The record also includes experimental measurements and structural context.
S17T (p.Ser17Thr) variant details
- p.Ser17Thr
- cosmic curated COSV99782
- TOPMed rs1951663808
- Uncertain significance
- Vascular malformation
- Missense
- ClinVar: Uncertain significance (Vascular malformation)
- UniProt: Uncertain significance
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.709