L6I (p.Leu6Ile) variant of KRAS (GTPase KRas)
L6I (p.Leu6Ile) in KRAS (GTPase KRas) is a missense change. Clinical records from EBI and UniProt describe it as uncertain significance. The record also includes experimental measurements and structural context.
L6I (p.Leu6Ile) variant details
- p.Leu6Ile
- gnomAD rs1296330213
- Uncertain significance
- Missense
- EBI: Variant of uncertain significance
- UniProt: Uncertain significance
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.626