L23Q (p.Leu23Gln) variant of KRAS (GTPase KRas)
L23Q (p.Leu23Gln) in KRAS (GTPase KRas) is a missense change. Clinical records from EBI and UniProt describe it as likely pathogenic. The record also includes experimental measurements and structural context.
L23Q (p.Leu23Gln) variant details
- p.Leu23Gln
- Ensembl rs730880472
- Likely pathogenic
- Missense
- EBI: Likely pathogenic
- UniProt: Likely pathogenic
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.0911