A18G (p.Ala18Gly) variant of KRAS (GTPase KRas)
A18G (p.Ala18Gly) in KRAS (GTPase KRas) is a missense change. Clinical records from EBI and UniProt describe it as pathogenic. The record also includes experimental measurements and structural context.
A18G (p.Ala18Gly) variant details
- p.Ala18Gly
- cosmic curated COSV55715
- Ensembl rs2135806030
- Pathogenic
- Missense
- EBI: Pathogenic
- UniProt: Pathogenic
- Structural context available
- abundance fitness from abundancePCA of KRAS block1: score -0.152