Y90C (p.Tyr90Cys) variant of KCNA2 (P16389)
Y90C (p.Tyr90Cys) in KCNA2 (P16389) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
Y90C (p.Tyr90Cys) variant details
- p.Tyr90Cys
- gnomAD 1-110604514-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.89
- CADD 28.30
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available