M66V (p.Met66Val) variant of KCNA2 (P16389)
M66V (p.Met66Val) in KCNA2 (P16389) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
M66V (p.Met66Val) variant details
- p.Met66Val
- gnomAD 1-110604587-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.27
- CADD 20.80
- PolyPhen-2 0.12
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available