L89W (p.Leu89Trp) variant of KCNA2 (P16389)
L89W (p.Leu89Trp) in KCNA2 (P16389) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
L89W (p.Leu89Trp) variant details
- p.Leu89Trp
- gnomAD 1-110604517-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.825
- REVEL 0.95
- CADD 28.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available