D21V (p.Asp21Val) variant of KCNA2 (P16389)
D21V (p.Asp21Val) in KCNA2 (P16389) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
D21V (p.Asp21Val) variant details
- p.Asp21Val
- TOPMed rs1649522435
- Missense
- Variant Prioritization Score for Impact Estimate 0.693
- REVEL 0.74
- CADD 26.30
- PolyPhen-2 0.50
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available