G64R (p.Gly64Arg) variant of JUP (Junction plakoglobin)
G64R (p.Gly64Arg) in JUP (Junction plakoglobin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G64R (p.Gly64Arg) variant details
- p.Gly64Arg
- gnomAD rs1555606934
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.17
- CADD 20.50
- PolyPhen-2 0.02
- SIFT 0.23
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available