E107D (p.Glu107Asp) variant of JUP (Junction plakoglobin)
E107D (p.Glu107Asp) in JUP (Junction plakoglobin) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
E107D (p.Glu107Asp) variant details
- p.Glu107Asp
- NCI-TCGA Cosmic COSV6027
- NCI-TCGA Cosmic COSV6028
- cosmic curated COSV60280
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.0913
- REVEL 0.10
- CADD 0.19
- PolyPhen-2 0.00
- SIFT 1.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available