F18L (p.Phe18Leu) variant of JUN (Transcription factor Jun)
F18L (p.Phe18Leu) in JUN (Transcription factor Jun) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data.
F18L (p.Phe18Leu) variant details
- p.Phe18Leu
- ExAC rs755842397
- TOPMed rs755842397
- gnomAD rs755842397
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.11
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the African/African-American population (allele frequency 2.4e-05)