G35R (p.Gly35Arg) variant of JAK1 (Tyrosine-protein kinase JAK1)
G35R (p.Gly35Arg) in JAK1 (Tyrosine-protein kinase JAK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
G35R (p.Gly35Arg) variant details
- p.Gly35Arg
- Ensembl rs1644804894
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- REVEL 0.56
- CADD 25.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available