W16S (p.Trp16Ser) variant of ITGA2B (Integrin alpha-IIb)
W16S (p.Trp16Ser) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
W16S (p.Trp16Ser) variant details
- p.Trp16Ser
- TOPMed rs755624202
- gnomAD rs755624202
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.41
- MetaLR 0.67
- MetaSVM 0.02
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available