W141G (p.Trp141Gly) variant of ITGA2B (Integrin alpha-IIb)
W141G (p.Trp141Gly) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
W141G (p.Trp141Gly) variant details
- p.Trp141Gly
- 1000Genomes rs559891307
- ExAC rs559891307
- TOPMed rs559891307
- gnomAD rs559891307
- Missense
- Variant Prioritization Score for Impact Estimate 0.602
- REVEL 0.62
- MetaLR 0.65
- MetaSVM 0.17
- CADD 32.00
- PolyPhen-2 0.82
- SIFT 0.02
- Most common in the 1KG:ITU population (allele frequency 0.0049)
- Structural context available