T73I (p.Thr73Ile) variant of ITGA2B (Integrin alpha-IIb)
T73I (p.Thr73Ile) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
T73I (p.Thr73Ile) variant details
- p.Thr73Ile
- gnomAD rs1260273450
- Missense
- Variant Prioritization Score for Impact Estimate 0.364
- REVEL 0.34
- MetaLR 0.73
- MetaSVM 0.56
- CADD 15.80
- PolyPhen-2 0.07
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available