T150A (p.Thr150Ala) variant of ITGA2B (Integrin alpha-IIb)
T150A (p.Thr150Ala) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
T150A (p.Thr150Ala) variant details
- p.Thr150Ala
- gnomAD rs1474292593
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.12
- MetaLR 0.34
- MetaSVM -0.82
- CADD 6.20
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available