S318L (p.Ser318Leu) variant of ITGA2B (Integrin alpha-IIb)

S318L (p.Ser318Leu) in ITGA2B (Integrin alpha-IIb) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely pathogenic in the context of Glanzmann thrombasthenia. The record also includes structural context.

S318L (p.Ser318Leu) variant details