R90K (p.Arg90Lys) variant of ITGA2B (Integrin alpha-IIb)
R90K (p.Arg90Lys) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
R90K (p.Arg90Lys) variant details
- p.Arg90Lys
- ExAC rs751857224
- TOPMed rs751857224
- gnomAD rs751857224
- Missense
- Variant Prioritization Score for Impact Estimate 0.201
- REVEL 0.24
- MetaLR 0.17
- MetaSVM -0.76
- CADD 4.91
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available