R3G (p.Arg3Gly) variant of ITGA2B (Integrin alpha-IIb)
R3G (p.Arg3Gly) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
R3G (p.Arg3Gly) variant details
- p.Arg3Gly
- Ensembl rs2048679968
- Missense
- Variant Prioritization Score for Impact Estimate 0.431
- REVEL 0.35
- MetaLR 0.62
- MetaSVM -0.21
- CADD 16.10
- PolyPhen-2 0.01
- SIFT 0.03
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available