P88A (p.Pro88Ala) variant of ITGA2B (Integrin alpha-IIb)
P88A (p.Pro88Ala) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
P88A (p.Pro88Ala) variant details
- p.Pro88Ala
- gnomAD rs2048646178
- Missense
- Variant Prioritization Score for Impact Estimate 0.693
- REVEL 0.71
- MetaLR 0.81
- MetaSVM 0.80
- CADD 25.60
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available