P36Q (p.Pro36Gln) variant of ITGA2B (Integrin alpha-IIb)
P36Q (p.Pro36Gln) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
P36Q (p.Pro36Gln) variant details
- p.Pro36Gln
- gnomAD rs1259889853
- Missense
- Variant Prioritization Score for Impact Estimate 0.412
- REVEL 0.33
- MetaLR 0.46
- MetaSVM -0.43
- CADD 17.40
- PolyPhen-2 0.09
- SIFT 0.23
- Most common in the Finnish in Finland (FIN) population (allele frequency 7.5e-05)
- Structural context available