P28T (p.Pro28Thr) variant of ITGA2B (Integrin alpha-IIb)
P28T (p.Pro28Thr) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P28T (p.Pro28Thr) variant details
- p.Pro28Thr
- Ensembl rs1015042585
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.20
- MetaLR 0.64
- MetaSVM -0.28
- CADD 12.30
- PolyPhen-2 0.06
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available