K149E (p.Lys149Glu) variant of ITGA2B (Integrin alpha-IIb)
K149E (p.Lys149Glu) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K149E (p.Lys149Glu) variant details
- p.Lys149Glu
- ExAC rs775222286
- gnomAD rs775222286
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.05
- MetaLR 0.20
- MetaSVM -0.95
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 0.80
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available