F41I (p.Phe41Ile) variant of ITGA2B (Integrin alpha-IIb)
F41I (p.Phe41Ile) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
F41I (p.Phe41Ile) variant details
- p.Phe41Ile
- TOPMed rs2048678390
- gnomAD rs2048678390
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.19
- MetaLR 0.23
- MetaSVM -0.91
- CADD 0.04
- PolyPhen-2 0.00
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available