A91V (p.Ala91Val) variant of ITGA2B (Integrin alpha-IIb)
A91V (p.Ala91Val) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A91V (p.Ala91Val) variant details
- p.Ala91Val
- ExAC rs764211480
- gnomAD rs764211480
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.22
- MetaLR 0.30
- MetaSVM -0.35
- CADD 23.30
- PolyPhen-2 0.10
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available