A91T (p.Ala91Thr) variant of ITGA2B (Integrin alpha-IIb)
A91T (p.Ala91Thr) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
A91T (p.Ala91Thr) variant details
- p.Ala91Thr
- gnomAD rs1362431939
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.03
- MetaLR 0.16
- MetaSVM -0.97
- CADD 17.50
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available