A25V (p.Ala25Val) variant of ITGA2B (Integrin alpha-IIb)
A25V (p.Ala25Val) in ITGA2B (Integrin alpha-IIb) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
A25V (p.Ala25Val) variant details
- p.Ala25Val
- ExAC rs753672121
- gnomAD rs753672121
- Missense
- Variant Prioritization Score for Impact Estimate 0.236
- REVEL 0.17
- MetaLR 0.61
- MetaSVM -0.46
- CADD 9.31
- PolyPhen-2 0.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available