V31M (p.Val31Met) variant of IRS2 (Insulin receptor substrate 2)
V31M (p.Val31Met) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
V31M (p.Val31Met) variant details
- p.Val31Met
- gnomAD rs1474364815
- Missense
- Variant Prioritization Score for Impact Estimate 0.557
- REVEL 0.48
- CADD 24.90
- PolyPhen-2 0.74
- SIFT 0.00
- Most common in the South Asian population (allele frequency 2.6e-05)
- Structural context available