S3N (p.Ser3Asn) variant of IRS2 (Insulin receptor substrate 2)
S3N (p.Ser3Asn) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S3N (p.Ser3Asn) variant details
- p.Ser3Asn
- Ensembl rs2138940046
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.11
- CADD 22.50
- PolyPhen-2 0.51
- SIFT 0.00
- Population evidence available
- Structural context available