S3G (p.Ser3Gly) variant of IRS2 (Insulin receptor substrate 2)
S3G (p.Ser3Gly) in IRS2 (Insulin receptor substrate 2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S3G (p.Ser3Gly) variant details
- p.Ser3Gly
- Ensembl rs2138940051
- Missense
- Variant Prioritization Score for Impact Estimate 0.253
- REVEL 0.09
- CADD 20.10
- PolyPhen-2 0.01
- SIFT 0.00
- Population evidence available
- Structural context available